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Ultra-rapid cycling bipolar affective disorder following a closed-head injury.
Brain Inj. 1993; 7(2):147-52 (ISSN: 0269-9052)
Zwil AS; McAllister TW; Cohen I; Halpern LR
A young adult with no prior history of affective disease suffered the onset of a rapid cycling bipolar illness, marginally responsive to psychotropic medications, following a mild closed-head injury, and persisting after the cognitive effects of the injury had resolved. A concurrence of findings on the neurological examination, neurobehavioural examination, SPECT scan, EEG and neuropsychological test battery suggested the presence of a diffuse cerebral injury with a predominance of left frontotemporal findings. This case demonstrates that a severe and disabling mood disorder may follow a mild head injury, and that its course may be independent of cognitive impairment and recovery.
- PreMedline Identifier: 8095835
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
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